Certified Transport Registered Nurse Certification Practice Exam

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What is the onset and duration of Etomidate when used for induction?

  1. 1-2 minutes onset, 30 minutes duration

  2. 5-10 minutes onset, 1-2 hours duration

  3. Less than 1 minute onset, 5-10 minutes duration

  4. 3-5 minutes onset, 5-10 minutes duration

The correct answer is: Less than 1 minute onset, 5-10 minutes duration

Etomidate is a short-acting intravenous anesthetic agent primarily used for induction of anesthesia, especially in patients where cardiovascular stability is crucial. The characteristic onset of Etomidate is typically less than one minute, which makes it highly effective for rapid sequence induction in emergency situations. This quick action is due to its high lipid solubility, allowing for rapid redistribution from the central nervous system. Regarding its duration, Etomidate has a relatively short effect lasting about 5 to 10 minutes. After the initial administration, the drug quickly metabolizes and redistributes, leading to a brief duration of action, which aligns well with the needs of fast-tracking patients through the anesthetic process. This profile of rapid onset coupled with a short duration explains why it is particularly favored in settings where quick recovery and minimal cardiovascular impact are necessary.