Certified Transport Registered Nurse Certification Practice Exam

What is the half-life of succinylcholine?

1. 2-3 minutes

2. 5-10 minutes

3. 15-20 minutes

4. 30-35 minutes

The correct answer is: 5-10 minutes

The half-life of succinylcholine is indeed primarily characterized by a duration of 2-3 minutes, which is the time it generally takes for the plasma concentration to decrease by half after administration. This rapid breakdown is attributed to its metabolism by plasma cholinesterase. While the duration of 5-10 minutes is close, it can be misleading, as the drug's effects typically wane significantly faster, often around the 2-3 minute mark. Succinylcholine is a depolarizing neuromuscular blocker used for rapid sequence intubation, and its quick onset and brief duration make it particularly useful in emergency situations. Understanding the pharmacokinetics of succinylcholine is crucial for transport nurses, as it informs decisions regarding timing for interventions and the management of patients receiving this medication. The rapid clearance allows for patient recovery relatively quickly, enhancing both safety and effectiveness of the transport process.